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July 1979

Cutaneous Melanoma in a Patient With Neurofibromatosis

Author Affiliations

From the Fox Chase Cancer Center and Temple University School of Medicine, Philadelphia (Drs Mastrangelo and Clark); the Thomas Jefferson University School of Medicine, Philadelphia (Dr Goepp); and Wilmington Medical Center, Wilmington, Del (Dr Patel).

Arch Dermatol. 1979;115(7):864-865. doi:10.1001/archderm.1979.04010070040020

Although neurofibromatosis and cutaneous melanoma are both diseases of neuroectodermal origin, reports of their association are rare. The case history of a patient with histologically documented neurofibromatosis and a nodular melanoma unrelated to a cafe-au-lait spot or congenital nevus is reported, and the literature reviewed. The appearance of only one patient with neurofibromatosis in a series of 900 patients with melanoma suggests that these diseases are probably not associated with greater frequency than that predicted by chance alone.

(Arch Dermatol 115:864-865, 1979)

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