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July 1979

Zebra-like Hyperpigmentation in an Infant With Multiple Congenital Defects

Author Affiliations

From the Departments of Dermatology (Drs Alimurung, Lang, and Willis) and Pathology (Dr Lapenas), Emory University, Atlanta.

Arch Dermatol. 1979;115(7):878-881. doi:10.1001/archderm.1979.04010070054026

An unusual pattern of zebra-like hyperpigmentation was observed in a black male infant with congenital defects that included an atrial septal defect, dextrocardia, auricular atresia, deafness, and growth retardation. The hyperpigmentation was strikingly linear and symmetrical and followed a dermatomal distribution, with involvement of the trunk and extremities. Results of histological, histochemical, and electron microscopic studies were normal except for an increase in the number of melanocytes in the bands of hyperpigmentation. This pigmentary anomaly appears to be transient and has faded to 50% of its original intensity. A review of the literature has not disclosed any similar cases.

(Arch Dermatol 115:878-881, 1979)

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