A mentally retarded female infant had abnormalities of the feet, hemiplegia, and an underlying nevus lipomatosus. To our knowledge, this represents the second reported case of marked folding of the skin; with an underlying nevus lipomatosus; this case demonstrated an association of this cutaneous disorder with multiple defects, including chromosomal abnormalities, which have not been previously reported.
(Arch Dermatol 115:978-979, 1979)
Gardner EW, Miller HM, Lowney ED. Folded Skin Associated With Underlying Nevus Lipomatosus. Arch Dermatol. 1979;115(8):978–979. doi:10.1001/archderm.1979.04010080042021