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September 1979

Maintenance Treatment for Psoriasis

Author Affiliations

Ghent, Belgium

Arch Dermatol. 1979;115(9):1033. doi:10.1001/archderm.1979.04010090001001

To the Editor.—  Psoralens plus long-wave ultraviolet radiation (PUVA) treatment for psoriasis is now widely used, possibly more in some European countries than in the United States. It is generally said that after an initial series of 20 to 30 irradiations, 95% or more clearing is obtained in 90% of patients. Most investigators then use a maintenance schedule consisting of one treatment every week or less, while others abstain from further irradiation.Treatment with PUVA was started in our institution in 100 patients with extensive psoriasis in the last quarter of 1976 and in 1977; two patients dropped out of the study for personal reasons and one failed to return after one irradiation because of "burning." The results can now be evaluated after an interval of one year or more.Of the 97 patients who completed the initial treatment, more than 95% clearing was obtained in 65 patients, 75% to

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