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September 1979

Touch Preparations in Diagnosis of Skin Disorders

Author Affiliations

Torrance, Calif

Irvine, Calif

Arch Dermatol. 1979;115(9):1034. doi:10.1001/archderm.1979.04010090002005

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To the Editor.—  Burg et al, in the March 1978 issue of the Archives (114:418-420, 1978), describe the diagnostic usefulness of enzyme cytochemical studies in a case of monocytic leukemia that appeared initially as dome-shaped cutaneous tumors. These studies were performed on frozen section material. We wish to point out the advantages of touch preparations over frozen sections in the investigation of lymphoreticular and hemopoietic disorders involving the skin.Touch preparations are made at the time of biopsy by touching the fresh tissue to clean, dry glass slides. At least ten slides should be prepared so that a battery of cytochemical stains may be performed. This is done by touching the slides delicately two or three times with the wet tissue. Three to five slides may be made from each cut surface of the skin. The slides are air-dried, not fixed in formaldehyde or alcohol. After the touch preparations are

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