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September 1979

Bullous Dermatosis and Systemic Lupus Erythematosus in a 15-Year-Old Boy

Author Affiliations

From the Department of Pathology, Lankenau Hospital, Philadelphia. Dr Jacoby is now with the Department of Pathology, New York University Medical Center, New York.

Arch Dermatol. 1979;115(9):1094-1097. doi:10.1001/archderm.1979.04010090044023

A 15-year-old boy had a bullous eruption suggestive of bullous pemphigoid and established systemic lupus erythematosus (SLE). Direct immunofluorescence studies of the bullae and adjacent skin revealed the linear deposition of IgG and complement localized to the basement membrane zone. Indirect immunofluorescence examination of the serum failed to reveal circulating basement membrane zone antibodies. The differential diagnosis of the bullous eruption is reviewed, and the problem of diagnosis in cases of coexistent bullous disease and SLE is discussed.

(Arch Dermatol 115:1094-1097, 1979)

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