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September 1979

Cutaneous Manifestations of Tumoral Calcinosis

Author Affiliations

From the Departments of Dermatology (Drs Pursley and Raimer) and Endocrinology (Drs Prince and Chausmer), University of Texas Medical Branch at Galveston.

Arch Dermatol. 1979;115(9):1100-1102. doi:10.1001/archderm.1979.04010090050025

We have followed up a large family in which seven members have tumoral calcinosis. One girl had the skin lesions of localized calcinosis cutis apart from the typical subcutaneous deposits of calcium. Like most persons with tumoral calcinosis, our patient had normal serum calcium concentrations; however, the serum phosphorus levels were greatly elevated. The familial occurrence and elevated serum phosphorus levels suggest the possibility of some as yet undefined, heritable metabolic defect as the underlying cause. The occurrence of tumoral calcinosis with localized calcinosis cutis is a rare association, and there has been only one other reported case to our knowledge. This report describes our patient and offers a brief discussion of tumoral calcinosis. The therapeutic response to the phosphate depletion regimen and topical steroids was disappointing in our case.

(Arch Dermatol 115:1100-1102, 1979)

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