On the basis of clinical features and histological findings, cutaneous manifestations of linear melorheostotic scleroderma are apparently derived from a localized proliferative disorder and are not secondary to bone changes. If the hypertrichosis has the same origin as the osteocutaneous changes, melorheostosis may represent a congenital disorder with both ectodermic and mesodermic components.
(Arch Dermatol 115:1233-1234, 1979)
Miyachi Y, Horio T, Yamada A, Ueo T. Linear Melorheostotic Scleroderma With Hypertrichosis. Arch Dermatol. 1979;115(10):1233–1234. doi:10.1001/archderm.1979.04010100053022
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: