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November 1979

The Early History of Tuberous Sclerosis

Author Affiliations

From the Department of Plastic and Reconstructive Surgery, The Cambridge Hospital (Dr Morgan) and the Harvard University Medical School (Dr Wolfort), Cambridge, Mass. Dr Morgan is now with the Department of Surgery, Section of Plastic Surgery, Fairfax Hospital, Falls Church, Va.

Arch Dermatol. 1979;115(11):1317-1319. doi:10.1001/archderm.1979.04010110023018

The early history of tuberous sclerosis can be traced from European wax models of the skin lesions in the 1830s to its recognition as a systemic disease by the early 1900s. There are various origins for the terms used for tuberous sclerosis, including Pringle's disease, Bourneville's disease, adenoma sebaceum, and epiloia. Since these terms are confusing and inaccurate, we urge that they no longer be used.

(Arch Dermatol 115:1317-1319, 1979)

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