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December 1979

Intracranial Calcifications and Dyskeratosis Congenita

Author Affiliations

From the Department of Pathology (Drs Mills and Cooper) and the Department of Dermatology (Drs Cooper, Beacham, and Greer), the University of Virginia Medical Center, Charlottesville.

Arch Dermatol. 1979;115(12):1437-1439. doi:10.1001/archderm.1979.04010120035015

We describe two brothers with dyskeratosis congenita and intracranial calcifications. The calcifications were massive, approximately symmetric, and showed a predilection for the basal ganglia and dentate nuclei. No underlying causes for this finding were identified. Idiopathic familial intracranial calcification of this type has been described, but an association with dyskeratosis congenita has not previously been observed.

(Arch Dermatol 115:1437-1439, 1979)

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