Atypical fibroxanthoma of the skin is a dermal lesion characterized by bizarre histologic features, but with benign biologic behavior.1 This article reports a case of atypical fibroxanthoma with prominent osteoid production, a phenomenon that has not previously been reported to my knowledge.
Report of a Case
A 47-year-old man had an ulcerated and painful nodule on the palmar aspect of the middle phalanx of the right third finger. Roentgenograms of the hand showed a soft tissue swelling at the site of the nodule without bony involvement. The lesion was excised.The nodule measured 1 cm at its largest dimension. The microscopic findings primarily involved the dermis; the lesion was composed of spindle and polyhedral cells lying in loose, fibrous tissue with no distinct organization (Fig 1). These cells had hyperchromatic nuclei with scattered miFig 1.—Cellular dermal lesion exhibiting no distinct pattern of cellular arrangement. Foci of osteoid production
Chen KTK. Atypical Fibroxanthoma of the Skin With Osteoid Production. Arch Dermatol. 1980;116(1):113–114. doi:10.1001/archderm.1980.01640250115030
Dermatology in JAMA: Read the Latest
Customize your JAMA Network experience by selecting one or more topics from the list below.