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February 1980

Angiosarcoma of the Nose

Author Affiliations

From the Department of Pathology, Veterans Administration Medical Center, and Louisiana State University Medical Center, New Orleans.

Arch Dermatol. 1980;116(2):226-227. doi:10.1001/archderm.1980.01640260102027

Angiosarcoma presenting as a tumor of the nose is extremely rare. Recently, such a case was encountered in our institution.

Report of a Case  A 72-year-old man was admitted to the hospital with a one-year history of a slowly enlarging lesion of his nose. Previously, he had been admitted to another hospital, where he had undergone multiple biopsies of the lesion. The biopsies were variously interpreted as pyogenic granuloma, lethal midline granuloma, and squamous cell carcinoma.On physical examination, the distal third of the nose showed a dark, firm, infiltrative lesion extending into the nasal cavities (Fig 1). The skin showed ulcerated areas, blood clots, and peripheral ill-defined purple-blue infiltrations. Palpable, hard lymph nodes, measuring up to 1.5 cm in diameter, were present in the submental and submandibular areas bilaterally. The rest of the physical findings were noncontributory. Roentgenograms and scans failed to show any evidence of distant metastasis.Because

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