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The authors had intended to include, in one volume, all of the information on tuberous sclerosis available up to the time of publication. In this endeavor they have been very successful. Not only has the literature been reviewed and culled thoroughly, but the authors have added many gems from their own clinical experiences.
In almost narrative form, the monograph begins with a history of tuberous sclerosis, starting with the initial observations of von Recklinghausen in 1862. The major discoveries in the tuberous sclerosis complex are recorded briefly and clearly. One by one, the modern concepts of this disease unfold.
Next, the authors review, describe, and analyze the cases of tuberous sclerosis made available to them at the Mayo Clinic, Rochester, Minn, for more than 30 years. Standards were high and the diagnosis of tuberous sclerosis was usually, but not always, based on the discovery of several clinical signs of the
Butterworth T. Tuberous Sclerosis. Arch Dermatol. 1980;116(2):234–235. doi:10.1001/archderm.1980.01640260110030
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