[Skip to Navigation]
March 1980

Basal Cell Carcinoma With Annular Leukoderma Mimicking Leukoderma Acquisitum Centrifugum

Author Affiliations

From the Department of Dermatology, University of Iowa College of Medicine, Iowa City.

Arch Dermatol. 1980;116(3):352-353. doi:10.1001/archderm.1980.01640270112027

Annular or circumferential leukoderma may accompany a variety of neuroectodermally and nonneuroectodermally derived skin lesions. The term "leukoderma acquisitum centrifugum" (LAC) has been used to describe cutaneous lesions in which a skin tumor, usually pigmented, is surrounded by a zone of hypopigmentation.1 Most of the lesions so defined have proven to be nevus cell nevi, hence the term "halo nevus" has frequently been used to describe the same process. An essential feature of LAC, however, is the presence of an inflammatory infiltrate in the dermis that is thought to mediate an antimelanin immunologic process. We report a case herein in which the centrally placed tumor, while appearing clinically to be halo nevus, was in fact a basal cell epithelioma.

Report of a Case  A 57-year-old man noticed a lesion on the left posterior part of his neck (Fig 1). He had initially been treated four months previously for multiple

Add or change institution