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June 1980

Halo Nevi and the Vogt-Koyanagi-Harada Syndrome: Manifestations of Vitiligo

Author Affiliations

From the Department of Dermatology, West Haven (Conn) Veterans Administration Medical Center (Dr Nordlund); the Department of Dermatology, Yale University School of Medicine, New Haven, Conn (Ms Forget and Dr Lerner); and the Massachusetts Eye and Ear Infirmary, Boston (Dr Albert).

Arch Dermatol. 1980;116(6):690-692. doi:10.1001/archderm.1980.01640300078024

• A 10-year-old boy with Vogt-Koyanagi-Harada syndrome had loss of pigment cells in the skin, the halo nevi, the retina, and probably the leptomeninges. The amount of inflammation that accompanied destruction of pigment cells varied greatly and seemed to determine whether the patient had symptoms from his vitiligo. This patient exhibited symptoms associated with loss of pigment cells in his skin and leptomeninges, but not from the destruction of the pigment cells in his eyes. We suggest that vitiligo is a disease that can be manifested in any tissue containing pigment cells and has a variable clinical expression.

(Arch Dermatol 116:690-692, 1980)

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