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July 1980

Localized Multicentric Bowen's Disease of the Scalp

Author Affiliations

From the Department of Dermatology, Louisiana State University School of Medicine, New Orleans.

Arch Dermatol. 1980;116(7):841. doi:10.1001/archderm.1980.01640310111030

Localized multicentric Bowen's disease of the genitalia has been reported previously, and in some instances, the disease has regressed spontaneously or with conservative therapy.1 We describe a patient with Bowen's disease in whom numerous lesions of the disease were confined solely to the scalp.

Report of a Case  A 54-year-old woman was first seen (by H.W.J.) in May 1976 complaining of a slowly enlarging but asymptomatic lesion on the scalp of ten years' duration. She had been treated elsewhere two years earlier with griseofulvin and iodochlorhydroxyquin without any response.The patient had had an unremarkable history; she had had no trauma to the scalp, previous x-ray therapy, arsenic ingestion, or substantial ultraviolet light exposure. Her only medication was conjugated estrogens. Her mother had died of carcinoma of the colon at the age of 73 years, and her maternal grandfather had had skin cancer.On examination, there was a 2.5

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