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September 1980

Cobalt Radiation-Induced Comedones

Author Affiliations

From the Division of Dermatology, University of California School of Medicine, San Diego.

Arch Dermatol. 1980;116(9):1073-1074. doi:10.1001/archderm.1980.01640330111028

Radiation-induced acneform lesions have been described after both radiation1-3 and cobalt4-6 therapy. This is a report of multiple comedo formation on the forehead and scalp of a patient who received cobalt therapy for a brain tumor.

Report of a Case  A 61-year-old man's condition was diagnosed as a tumor in the right side of the middle of the brain in January 1978. Although no tissue diagnosis was made, findings on brain scan suggested that the tumor was a low-grade glioblastoma. The patient had been receiving 100 mg of phenytoin sodium every 12 hours and 150 mg of phenobarbital at bedtime during the previous three years for a focal seizure disorder. During a ten-week interval, during August and September 1978, he was given 30 radiation treatments to the head with cobalt 60 (6 meV) through opposing bilateral portals with a field size of 10 × 16 cm. The treatment

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