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September 1980

Pretibial Myxedema: Recurrence After Skin Grafting

Author Affiliations

From the Department of Dermatology, Thomas Jefferson University, Jefferson Medical College, Philadelphia.

Arch Dermatol. 1980;116(9):1076-1077. doi:10.1001/archderm.1980.01640330114030

Pretibial myxedema is recognized as a type of localized myxedema that usually occurs on the anterior lower part of the legs and is often associated with thyroid disease. The lesions have been known to occur or become worse after thyroid surgery or radiation. We present here a case of a patient who sought surgical intervention for his disease.

Report of a Case  A 28-year-old man's condition was diagnosed as hyperthyroidism in 1974, and he received subsequent iodine 131 thyroid ablation. Three years later, the patient noted single, painless, pink nodules in the pretibial areas of each leg. Excisional biopsy specimens of the lesions were reported as "myxomas of the skin." The lesions recurred, and the patient was referred to a plastic surgeon for wide excision and splitthickness skin grafting of both pretibial areas. Three months after excision and grafting, there was evidence of recurrence of leg lesions within the graft

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