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November 1980

Experimental Skin Grafts and Transplantation Immunity

Arch Dermatol. 1980;116(11):1317. doi:10.1001/archderm.1980.01640350107027

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


For reasons of technical convenience, modern transplantation biology (and in particular its immunologic aspects) originated very largely from studies on experimental and therapeutic skin grafts. This monograph is written by a well-known transplantation biologist and a distinguished plastic surgeon who, in collaborative and other studies spanning several decades, have made major contributions to our understanding of the biology of skin grafting. The book deals principally with practical and observational aspects, deliberately omitting any attempts to cover in other than the briefest manner the complex details of immunogenetics and the modus operandi of allograft rejection.

It covers in detail such important topics as the revascularization of various types of skin grafts and the variety of ingenious methods that have been developed to determine the survival end-points of allografts, the various patterns of rejection that overtake allografts depending on the genetic relationship between donor and host, the dosage of the grafted

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