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January 1981

Possible Dysglobulinemia and Grover's Disease

Author Affiliations

Cambridge, Mass

Arch Dermatol. 1981;117(1):3. doi:10.1001/archderm.1981.01650010007008

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To the Editor.—  In the May issue of the Archives (1980;116:515) Millns et al described a patient who had Grover's disease and positive cutaneous immunofluorescent microscopy findings. They commented that their patient had a "benign monoclonal gammopathy."Recently, a patient whom I had treated 20 years ago for proved allergic contact dermatitis was referred to me at the age of 73 years with a peculiar papular eruption and chronic lymphatic leukemia. The patient complained of severe itching, but he said it was not severe enough to prevent sleep.He had had a knee replacement operation in 1977 before the onset of his disease for degenerative and rheumatoid arthritis. In 1979, a WBC count of 12,200/cu mm led to a hematologic investigation. His platelet count was 70,000/cu mm. The serum electrophoretic pattern was normal. The hepatitis antigen was absent in the serum. Rheumatoid arthritis factor was 1:280. Bone marrow studies confirmed

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