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January 1981

Necrolytic Migratory Erythema Without Glucagonoma

Author Affiliations

Lyons, France

Arch Dermatol. 1981;117(1):4. doi:10.1001/archderm.1981.01650010008010

To the Editor.—  In the December 1979 issue of the Archives (115:1429-1432), Goodenberger et al described two patients with necrolytic migratory erythema without glucagonoma. They stated that reported cases of this eruption have been invariably associated with glucagon-secreting islet cell tumors of the pancreas. However, they forgot to quote a previous description of a patient with mucocutaneous aspects of this syndrome, but without diabetes or a pancreatic tumor.1,2 To repair this omission, it would be useful to summarize this observation briefly.

Report of a Case.—  Since 1961, a 38-year-old man had suffered from chronic pancreatitis, accompanied by bouts of abdominal pain that lasted from three to 15 days. Roentgenographic examination revealed pancreatic calcifications. Serum glucose levels were normal.Since that time, the patient had also had a dermatosis, which had been preceded by diffuse pruritus and bouts of digestive trouble. The cutaneous eruption was characterized by arcuate or serpiginous

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