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February 1981

Hyperthermia in Severe Cases of Psoriasis

Arch Dermatol. 1981;117(2):64. doi:10.1001/archderm.1981.01650020004007

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To the Editor.—  I read with interest your editorial entitled "The Heat's On" in the August 1980 Archives (116:885-887). Thirty years ago, when I was a dermatology resident at Case Western Reserve, Cleveland, Drs George Binkley and Herbert Johnson used hyperthermia successfully for severe cases of psoriasis.Hospitalized patients were given two intravenous doses of killed typhoid bacilli at half-hour intervals; 10 to 15 million units at first, and then (usually) increasing amounts (depending on the fever obtained) every few days for three or four courses of treatment. A temperature of approximately 39 †C was sought. The psoriasis would often go into remission for several months. This therapy also helped psoriatic arthritis.

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