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March 1981

Retinoids, Cancer, and the Skin

Author Affiliations

From the Department of Dermatology, University of California School of Medicine (Dr Williams), and the Dermatology Service, Veterans Administration Medical Center, San Francisco (Dr Elias).

Arch Dermatol. 1981;117(3):160-180. doi:10.1001/archderm.1981.01650030038018

• Vitamin A and its newly developed synthetic analogues recently have been demonstrated to have profound effects on disorders of keratinization, sebaceous gland function, and cancer. In separate sections of this article, we review the history, chemistry, metabolism, mechanism of action, toxicity, and clinical applications of both the naturally occurring and synthetic retinoids.

(Arch Dermatol 1981;117:160-180)

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