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May 1981

Skin Reactions to Carbamazepine

Author Affiliations

From the Department of Medicine, Welsh National School of Medicine, Heath Park, Cardiff, Great Britain.

Arch Dermatol. 1981;117(5):273-275. doi:10.1001/archderm.1981.01650050029015

• Three patients with a generalized eruption caused by carbamazepine are described. Two reactions were eczematous, and one was lichenoid in nature. Oral challenge with the drug reproduced the skin disorder in each of these patients. Immunofluorescence microscopy studies demonstrated that in four out of six other subjects taking carbamazepine, there were deposits of immunoglobulins in the skin.

(Arch Dermatol 1981;117:273-275)

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