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September 1981

Facial Granuloma in a Patient Treated With Clofazimine

Author Affiliations

From the Department of Medicine, Ahmadu Bello University Hospital, Zaria, Nigeria. Dr Jacyk is now with the German Leprosy Relief Association, Nairobi, Kenya.

Arch Dermatol. 1981;117(9):597-598. doi:10.1001/archderm.1981.01650090079035

Facial granuloma is a well-defined entity, clinically characterized by raised, painless, brown-red plaques that occur singly or in groups on the face. Extrafacial lesions are seldom seen. The condition ocurs in both sexes, mainly in middle-aged persons. It rarely develops in persons of African origin; only one case had been reported in an American black person.1 Treatment of facial granuloma is seldom successful, and spontaneous involution is rare.

I report herein a typical case of facial granuloma in a Nigerian who responded to treatment with clofazimine. To my knowledge, this case is the first reported instance of facial granuloma in an African and the first to be successfully treated with clofazimine.

Report of a Case  A 36-year-old Nigerian man, apparently in good health, had facial lesions of three years' duration as of January 1979. On physical examination, there were three sharply outlined, raised, erythematous lesions with irregular surfaces. The

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