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This book is the seventh in a series that attempts the immense task of covering all aspects of immunology. This volume is of particular interest because it tries to bridge a gap between two disciplines—immunology and dermatology. The interface between these two sciences has only recently been defined, and this book makes a major contribution by demonstrating the integral role the immune system plays in dermatologic diseases. The authors have been selected from among the major specialists in each topic covered. The book is extensive and has a great deal to offer both the practicing dermatologist and the clinical immunologist. As with any book written by many authors, the quality and readability of the chapters vary with the individual styles of the authors. Of particular interest were the chapters on complement, the HLA system in dermatologic disease, the role of Langerhans' cells in cutaneous reactions, malignant melanoma, transplantation immunology, and