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January 1982

Nevus Comedonicus Syndrome

Arch Dermatol. 1982;118(1):1. doi:10.1001/archderm.1982.01650130005001

To the Editor.—  In the February 1981 Archives (117:86-88), Barsky et al reported four cases of nevus comedonicus (NC) in which the histologic changes of epidermolytic hyperkeratosis were seen in the wall of the comedones.The article states that "various authors have reported on the association of NC with several other histological phenomena but these did not occur in the individual comedo." I would like to call attention to the report of Bleiberg and Brodkin1 describing the microscopic findings of buds of proliferating basal cell epithelioma projecting into the dermis from the cyst wall of a comedo (epidermoid cyst) in a patient with linear basal cell nevus and comedones. It is evident that the histologic variants seen in NC parallel those seen in epidermal nevi (epithelial nevi).Barsky et al concur with the opinion of Degos et al2 that all epidermal nevi are basically alike. This point is

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