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February 1982

Kyrle's Disease in Patients With Chronic Renal Failure

Author Affiliations

From the Divisions of Dermatology (Drs Hood, Hardegen, and Nigra) and Nephrology (Dr Zarate), Washington Hospital Center and Georgetown University Hospital (Dr Gelfand), Washington, DC. Dr Hood is now with the Department of Dermatology, The Johns Hopkins Medical Institutions, Baltimore.

Arch Dermatol. 1982;118(2):85-88. doi:10.1001/archderm.1982.01650140017009

• Hyperkeratosis follicularis et parafollicularis in cutem penetrans, or Kyrle's disease, is a rare dermatologic entity with distinctive clinical and histopathologic features. Over a two-year period, nine cases of Kyrle's disease were observed among 200 patients receiving hemodialysis for chronic renal failure. This observation suggests an association between Kyrle's disease and renal disease that, to our knowledge, has not previously been reported.

(Arch Dermatol 1982;118:85-88)

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