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March 1982

Multiple Minute Digitate Hyperkeratoses or Disseminated Spiked Hyperkeratosis

Arch Dermatol. 1982;118(3):142. doi:10.1001/archderm.1982.01650150004004

To the Editor.—  I read with interest the article in the July 1981 Archives on disseminated spiked hyperkeratosis. In their review of the literature, Frenk et al failed to disclose an earlier description of such an entity.I would like to call to their attention the reports of Goldstein1 and Yoon and Gibbs2 on multiple minute digitate hyperkeratoses. Both disseminated spiked hyperkeratosis and multiple minute digitate hyperkeratoses seem similar in that they consist of multiple discrete spiny protrusions that (1) develop in the second or third decade of life, (2) are essentially symptom free, (3) are 3 mm or less in length and 2 mm or less in diameter, (4) arise from normal skin and, when mechanically removed, separate above the skin line leaving unaltered bases, and (5) on performance of a biopsy show focal hyperkeratosis, mild acanthosis, a variable granular layer, and an essentially normal dermis.