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May 1982

Cutaneous Calcinosis of Scleroderma: Successful Treatment With Intralesional Adrenal Steroids

Author Affiliations

From the Department of Dermatology, Case Western Reserve University, Cleveland.

Arch Dermatol. 1982;118(5):366-367. doi:10.1001/archderm.1982.01650170080035

In 1979, Hazen and Askari1 described two patients who had a unique form of localized scleroderma. Both patients had prominent sclerodermatous changes of the face and scalp associated with hair loss, beaking of the nose, extensive calcinosis of the face, and persistent ulcers in the areas of calcinosis. Multiple treatments had been tried with little or only temporary improvement. We now wish to report almost complete resolution of the calcinosis and healing of the associated cutaneous ulcerations in one of the patients after repeated injections of intralesional steroids. The other patient was unavailable for follow-up.

Report of a Case  In 1976, an 83-year-old woman had had a 15-year history of progressive tightening of the facial and scalp skin and anterior scalp alopecia and a two-year history of calcinosis in the preauricular and zygomatic areas and on the neck. In areas of cutaneous calcification, painful, large ulcerations had developed, and

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