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July 1982

Malignant Angioendotheliomatosis Proliferans Treated With Doxorubicin

Author Affiliations

From the Departments of Dermatology (Drs Keahey and Bondi), Hematology and Oncology (Dr Guerry), and Pathology (Dr Tuthill), Hospital of the University of Pennsylvania, Philadelphia.

Arch Dermatol. 1982;118(7):512-514. doi:10.1001/archderm.1982.01650190066022

• An 84-year-old man was examined for progressive pain, edema, and infiltrating skin lesions on his lower extremities. A skin biopsy specimen confirmed the suspected diagnosis of angioendotheliomatosis proliferans. The clinical course and histologic changes suggested the malignant form of this disease. Treatment with intravenous doxorubicin hydrochloride caused a complete clinical remission.

(Arch Dermatol 1982;118:512-514)

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