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August 1982

Hydroa Vacciniforme: Diagnosis and Therapy

Author Affiliations

From the Department of Dermatology, Veterans Administration Hospital, West Haven, Conn (Drs Goldgeier and Nordlund); and Yale University Medical Center, New Haven, Conn (Drs Lucky, Sibrack, McCarthy, and McGuire).

Arch Dermatol. 1982;118(8):588-591. doi:10.1001/archderm.1982.01650200056017

• Hydroa vacciniforme is a rare, chronic photodermatosis with onset in childhood. Multiple exposures to UV-A reproduced the symptoms and the vesicular and scarring lesions typical of the sun-induced disease in our patient. Treatment with hydroxychloroquine sulfate, but not indomethacin, reduced the photosensitivity both to sunlight and to artificial UV-A light. Serum complement levels were low while the disease was active and returned to normal after treatment of the patient with hydroxychloroquine.

(Arch Dermatol 1982;118:588-591)

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