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February 1983

Histiocytosis X in Two Adults: Treatment With Topical Mechlorethamine

Author Affiliations

From the Department of Medicine, Division of Dermatology, St Michael's Hospital, University of Toronto.

Arch Dermatol. 1983;119(2):157-161. doi:10.1001/archderm.1983.01650260065021

• Two adult patients with skin lesions typical of histiocytosis X were treated topically with mechlorethamine hydrochloride. In the patient whose disease was limited to the skin, a sustained remission was induced, but in the patient with extensive systemic disease, cutaneous remission lasted only six weeks.

(Arch Dermatol 1983;119:157-161)

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