To the Editor.—
Epidermolytic hyperkeratosis is a nonspecific dermal process with a distinctive histopathologic picture described as (1) an isolated and/or incidental finding associated with acquired solitary skin lesions,1-3 (2) occurring as the main histologic pattern of bullous congenital ichthyosiform erythroderma,2,4 and (3) appearing in congenital epidermal nevi (disseminated, linear, and circumscribedFig 1.—Photomicrograph of superficial basal cell carcinoma. To right, focus of epidermolytic hyperkeratosis is observed (hematoxylin-eosin, ×80). types).2,3,5 I saw an unusual case of epidermolytic hyperkeratosis associated with basal cell carcinoma.
Report of a Case.—
A 65-year-old woman was seen with a lesion of several months' duration on the anterior part of the right leg. On examination, it was an erythematous scaly patch, 3 × 1 cm in diameter. Findings from a general physical examination and results of routine laboratory studies were otherwise normal. The clinical diagnosis was basal cell carcinoma. Histopathologic examination of the