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May 1983

Haber's Syndrome or Dowling-Degos Disease?

Author Affiliations

Department of Dermatology Miyazaki Medical College 889-16 Kiyotake, Japan

Arch Dermatol. 1983;119(5):365-366. doi:10.1001/archderm.1983.01650290005005

To the Editor.—  On the three cases of Haber's syndrome (HS) we reported in the June 1981 Archives (117:321-324), Crovato and Rebora wrote in the April 1982 Archives (118:214) that Dowling-Degos disease (DDD) should be seriously considered in the differential diagnosis of HS. In a reply to Crovato and Rebora, I said that HS and DDD are different entities, since all cases of DDD, originally reported by Jones and Grice,1 had had reticulate pigmentation, while our cases of HS did not. I recently observed four cases of DDD in one family; one of these patients did not have reticulate pigmentation. Therefore, reticulate pigmentation is not a prerequisite for the diagnosis of DDD.I have changed my view. In addition to the common histologic feature of epidermal downgrowths, I now think HS may be the same as DDD for the following reasons:

  1. Both DDD and HS are slowly

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