• Ultrastructural examination of expressed "black" open comedones did not disclose any single melanosomes or melanosome complexes. If there is any melanin present in comedonal plugs, the amount is minimal, and it cannot be the source of the black color.
(Arch Dermatol 1983;119:567-569)
Zelickson AS, Mottaz JH. Pigmentation of Open Comedones: An Ultrastructural Study. Arch Dermatol. 1983;119(7):567–569. doi:10.1001/archderm.1983.01650310029005
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