[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.236.187.155. Please contact the publisher to request reinstatement.
Article
August 1983

Serum Triglyceride Elevation Following High-Dose Vitamin A Treatment for Pityriasis Rubra Pilaris

Author Affiliations

From the Division of Dermatology, the Department of Medicine, Duke University Medical Center, Durham, NC.

Arch Dermatol. 1983;119(8):675-676. doi:10.1001/archderm.1983.01650320049015
Abstract

• We describe two patients with pityriasis rubra pilaris in whom hypertriglyceridemia developed following the oral administration of high-dose vitamin A (retinol). The effects of transient hypertriglyceridemia are unknown, as both patients tolerated high-dose vitamin A therapy with minor, if any, other side effects. Both patients had minimal clinical improvement with this therapy. Patients being treated with 1,000,000 IU of vitamin A each day for ten to 14 days should have frequent determinations of serum lipid levels and liver function during the period of drug administration.

(Arch Dermatol 1983;119:675-676)

×