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August 1983

Demonstration of Treponema pallidum in a Cutaneous Gumma by Indirect Immunofluorescence

Arch Dermatol. 1983;119(8):677-680. doi:10.1001/archderm.1983.01650320051016

Treponema pallidum was demonstrated in a cutaneous, tertiary syphilitic lesion by indirect immunofluorescence microscopy, but not by darkfield microscopy illumination or silver stain. The numerous organisms observed by this method may help explain the histologically vigorous tissue reaction in tertiary syphilis, despite the scarcity of organisms demonstrable by other methods.

(Arch Dermatol 1983;119:677-680)