We report herein a case of acanthosis nigricans in a young man with the adrenogenital syndrome who, in addition, had hyperlipoproteinemia type IV, mild diabetes mellitus, and a double, left-sided renal pelvis and ureter. To our knowledge, this is the first report of acanthosis nigricans in conjunction with the adrenogenital syndrome.
Report of a Case
A 21-year-old man was referred to the Beilinson Medical Center, Petah Tiqva, Israel, because of a dermatosis that had been diagnosed as acanthosis nigricans. It had first appeared in childhood when the patient had begun to suffer from obesity and growth retardation.On hospital admission, the patient was extremely obese and of short stature (weight, 123 kg; height, 150 cm). His BP was normal. He was of masculine build with a masculine hair pattern on the face and the pubis. On examination of the genital area, a 3- to 4-cm clitoris was found. On both
Weissman-Katzenelson V, David M, Grunwald MH, Feuerman EJ. Acanthosis Nigricans: In Association With the Adrenogenital Syndrome, Hyperlipoproteinemia Type IV, and Congenital Malformation of the Urinary Tract. Arch Dermatol. 1983;119(11):953–954. doi:10.1001/archderm.1983.01650350081023
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: