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December 1983

Guttate Psoriasis, Glomerulonephritis and Streptococcal Infection

Author Affiliations

The Skin Hospital Quay Street Manchester M3 3HL, England Katherine Whale, MRCPath Monsall Hospital Manchester

Dryburn Hospital Durham, England

Arch Dermatol. 1983;119(12):956. doi:10.1001/archderm.1983.01650360002002

To the Editor.—  In response to our letter in the March Archives (1982;118:141) on guttate psoriasis and renal disease, Belew reported (1983;119:3) that in her area guttate psoriasis is associated with the locally common and also potentially nephritic group A streptococcus of serotype Ml, Tl. In a recent study we found group A streptococci in nine of 34 patients with acute guttate psoriasis and four of 30 patients with acute guttate flares complicating chronic psoriasis. More than half the patients seen and all of those from whom group A streptococci were isolated had serologic evidence of recent streptococcal infection. The 13 streptococcal isolates were of ten different serotypes, the majority of which were common in the community at the time of the study. The serotype Ml, T1 was found in two patients. Our findings suggest that the ability of the group A streptococcus to trigger guttate psoriasis is not type