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December 1983

Gluten-Free Diet in Patients With Dermatitis Herpetiformis: Effect on the Occurrence of Antibodies to Reticulin and Gluten

Author Affiliations

From the Department of Dermatology (Dr Ljunghall) and the Institute of Clinical Bacteriology (Drs Scheynius and Forsum), Uppsala (Sweden) University; and the National Bacteriological Laboratory, Stockholm (Drs Jonsson and Schilling).

Arch Dermatol. 1983;119(12):970-974. doi:10.1001/archderm.1983.01650360016006

• In a prospective study of 51 patients with dermatitis herpetiformis (DH), the occurrence of antibodies against reticulin and gluten was investigated and the influences of gluten-free, gluten-restricted, and normal diets on the persistence of these antibodies were compared. After a period extending from 11 to 47 months, none of the patients who were eating a gluten-free diet had reticulin or gluten antibodies. The patients eating a normal diet had the same incidence of reticulin autoantibodies at the end of the study as at its beginning, and gluten antibodies developed in some additional patients during the follow-up period. Thus, we have shown that the elimination of gluten from the diet of patients with DH has an important influence on the occurrence of antibodies to both reticulin and gluten.

(Arch Dermatol 1983;119:970-974)

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