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January 1984

Comparison of Phototherapy (UV-B) and Photochemotherapy (PUVA) for Clearing and Maintenance Therapy of Psoriasis

Author Affiliations

From the Departments of Dermatology (Drs Boer, Schothorst, and Suurmond) and Medical Statistics (Dr Hermans), University Hospital, Leiden, the Netherlands.

Arch Dermatol. 1984;120(1):52-57. doi:10.1001/archderm.1984.01650370058011

• One hundred eighty-three patients with psoriasis were treated with UV-B irradiation or oral methoxsalen plus longwave UV light (PUVA). Patients treated with PUVA, in the initial and maintenance period, achieved in general a higher therapeutic score (95% to 100% clearance) than those receiving UV-B therapy. However, taking 80% to 100% improvement as criterion, no difference was found between initial UV-B and PUVA therapy, if less than 50% of the skin surface was affected by psoriasis. If more than 50% of the skin was involved, PUVA was better than UV-B therapy. The maintenance treatment frequency for the UV-B—treated patients for more than a year seemed to be higher than for PUVA-treated patients. A positive correlation was found between response to sunbathing (questionnaire survey) and the response to UV-B phototherapy. An extra UV-B treatment to the leg lesions appeared useless.

(Arch Dermatol 1984;120:52-57)

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