• This study investigated the histogenesis of the Kaposi's sarcomas occurring in young homosexual men. Paraffin sections of seven tumors were stained for factor VIII-related antigen by the unlabeled peroxidase antiperoxidase method. Both the spindle cell component and the cells lining vascular channels contained factor VIII-related antigen, a marker for endothelial cells. Our study supports the hypothesis that both components of Kaposi's sarcoma are of endothelial cell origin.
(Arch Dermatol 1984;120:180-182)
Thomas J. Flotte, Virgil A. Hatcher, Alvin E. Friedman-Kien. Factor VIII-Related Antigen in Kaposi's Sarcoma in Young Homosexual Men. Arch Dermatol. 1984;120(2):180–182. doi:10.1001/archderm.1984.01650380040007