Leiomyosarcoma of the Small Intestine Metastatic to the Umbilicus

We describe a patient with leiomyosarcoma of the small intestine in whom the development of a Sister Mary Joseph nodule of the umbilicus was the primary evidence of advancing disease. The appearance of a metastatic umbilical nodule is recognized as a sign of poor prognosis; our patient died within two years after the onset of this lesion.