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May 1984

Lichen Planus in Monozygotic Twins

Author Affiliations

Division of Dermatology Children's Memorial Hospital 2300 Children's Plaza Chicago, IL 60614

Arch Dermatol. 1984;120(5):580. doi:10.1001/archderm.1984.01650410022011

To the Editor.—  We recently had an opportunity to examine 11-year-old monozygotic twin girls with concurrent lichen planus. One twin had the onset of a moderately pruritic eruption that evolved during several weeks' time to involve her trunk and extremities, sparing only her face. Within several weeks, her identical twin sister experienced the same symptoms and skin changes. The girls were otherwisePapular lesions of lichen planus on anterior trunk of both twins. healthy and had had no constitutional symptoms associated with their eruption. They were seen at Children's Memorial Hospital, Chicago, one year after the onset of their disease (Figure) when skin biopsy confirmed the clinical diagnosis of lichen planus.The cause of lichen planus remains unknown today, just as it was when Erasmus Wilson wrote his initial work on the subject in 1869. Although an infectious cause has been suggested by some authors, no data to support that

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