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July 1984

Angioimmunoblastic Lymphadenopathy Followed by Kaposi's Sarcoma

Author Affiliations

From the Departments of Internal Medicine (Dr Kluin-Nelemans), Pathology (Dr Elbers), and Dermatology (Dr Ramselaar), St Antonius Hospital, Nieuwegein, the Netherlands.

Arch Dermatol. 1984;120(7):958-959. doi:10.1001/archderm.1984.01650430148025

Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is an uncommon, nonneoplastic, lymphoproliferative disorder.1 Progression into non-Hodgkin's lymphoma takes place in 10% to 30% of the cases, but an association with other malignant neoplasms occurs only rarely.1,2 Previously the occurrence of Kaposi's sarcoma in patients with AILD has been described in three patients.3-5 In this article, a fourth patient is described in whom the unique combination of both diseases was found in one lymph node.

Report of a Case  Plaques and nodules developed on both feet of a 76-year-old man six weeks before he was admitted to the hospital. During the previous months, he had experienced bouts of fever with generalized pruritus. For the past year he had taken aminophylline and doxycycline hydrochloride for chronic bronchitis. Physical examination disclosed firm, movable, nontender lymph nodes, ranging in size from 1 to 3 cm in diameter, that were palpated in the submandibular,

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