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August 1984

Low-grade Clear Cell Eccrine Carcinoma

Author Affiliations

From the Departments of Pathology (Drs Cooper and Robinson) and Dermatology (Drs Cooper and Greer), University of Virginia, Charlottesville.

Arch Dermatol. 1984;120(8):1076-1078. doi:10.1001/archderm.1984.01650440106032

• Two patients had facial tumors that had a distinctive microscopic appearance. Each consisted of multiple nests of glycogen-filled clear cells dispersed in the dermis and associated with a hyalinized, collagenous stroma. There were also ductular features suggestive of eccrine differentiation. The lesions had a locally infiltrative microscopic appearance, and one involved the subcutaneous fat and skeletal muscle. Although neither tumor has recurred following excision, we believe that they are low-grade eccrine carcinomas and that they may represent a distinctive, albeit rare, subtype of adnexal neoplasm.

(Arch Dermatol 1984;120:1076-1078)

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