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August 1984

Juvenile Pemphigus Vulgaris

Author Affiliations

From the Division of Dermatology (Drs Lynde and Ongley) and the Department of Pediatrics (Dr Rigg), University of British Columbia, Vancouver, Canada.

Arch Dermatol. 1984;120(8):1098-1099. doi:10.1001/archderm.1984.01650440128035

Pemphigus vulgaris (PV), usually considered to be a disease of middle age, is becoming increasingly recognized in children. Twenty-two cases of PV in patients younger than 20 years of age have been reported since 1955. However, PV is not always considered early in the differential diagnosis of vesiculobullous disorders in younger patients and this may result in an unnecessary delay in diagnosis.

We report herein a case of PV in a 15-year-old boy that satisfies currently acceptable clinical, histopathologic, and immunologic criteria for the diagnosis of this disease. Our purpose is to emphasize that this disease may occur in juvenile patients and should be considered in the differential diagnosis of erosive lesions of the oral mucosa in such patients. In addition, the success of therapy with prednisone and azathioprine recorded in our patient is of interest, since therapy can be difficult in this group of patients.

Report of a