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December 1984

Collagen in Health and Disease

Arch Dermatol. 1984;120(12):1622. doi:10.1001/archderm.1984.01650480084026

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The comprehensive presentation of collagen as it relates to medical and scientific interests is an ambitious and difficult undertaking. It is also one that this book accomplishes almost without fail. The editors present the basic biophysical, biochemical, and cell biology aspects in the first half of the book, followed by a most valuable collection of chapters discussing the collagens of specific tissues. In general, the chapters are well written and uniformly satisfying in both content and length and should prove useful for the intended readership.

Following an introductory chapter and one dealing with proteins containing collagenous sequences, the basic science of collagen is expounded in sections on structure, biomechanical properties, synthesis, and post-translational modifications, followed by a number of chapters discussing collagen turnover, specific degradative pathways, and the modification of synthesis and degradation. This latter section is a particularly strong point of the work; however, one should combine readings in

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