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March 1985

Mule Spinner's Disease

Author Affiliations

From the Sections of Dermatology (Drs Castiglione and Dimond) and Urology (Dr Selikowitz), Veterans Administration Hospital, White River Junction, Vt, and Dartmouth-Hitchcock Medical Center, Hanover, NH. Dr Castiglione is now in private practice in New Haven, Conn.

Arch Dermatol. 1985;121(3):370-372. doi:10.1001/archderm.1985.01660030092026

• Mule spinner's disease represents the occurrence of scrotal cancer in cotton textile workers exposed to mineral oils on a long-term basis while working on a machine called "the mule." We describe a 66-year-old cotton textile worker who had frequent scrotal contact with mineral oils and later had multiple squamous cell carcinomas of the scrotum develop. He also had a variety of other keratotic lesions develop on the scrotum that histopathologically demonstrated features of verruca, lichenoid keratoses, and squamous cell carcinomas in situ. We have termed these lesions mule spinner's keratoses.

(Arch Dermatol 1985;121:370-372)